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PS 4326-2026
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Tobacco and tobacco products — Determination of tobacco-specific nitrosamines in tobacco products — Method using LC-MS/MS
Committee:
Tobacco and Tobacco Products
Sector:
Food and Agriculture
Available Standards
Original Standard
إنجليزي (English)
25
Page
2026
International Classification for Standards (ICS)
| Code | Classification |
|---|---|
| 65.160 | Tobacco, tobacco products and related equipment |
Adopted Standards
| Standards / Amendment / Corrigendum | |
|---|---|
| 1 | ISO 21766:2021 |
Replacement Sequence
| Replaces |
|---|
| PS 4326-2021 |
Scope
This document specifies a method for the quantification of four tobacco specific nitrosamines (TSNAs) in tobacco and the following tobacco products: cigarettes, cigars and smokeless tobacco products using reversed phase high performance liquid chromatography with tandem mass spectrometry (LC-MS/MS). The TSNAs determined with this method are:
N-nitrosonornicotine (NNN),
N-nitrosoanatabine (NAT),
N-nitrosoanabasine (NAB) and,
4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone (NNK).